Trithorax group (TrxG)

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:amendedBy chromatin structure
histone H3 lysine 4 (H3K4)
gptkbp:associatedWith gptkb:cancer
leukemia
gptkbp:contains gptkb:BRM
gptkb:CBP
gptkb:SWI/SNF_complex
gptkb:ASH1
gptkb:MLL1
gptkb:Trithorax_(Trx)
gptkbp:discoveredIn Drosophila genetic studies
gptkbp:enemyOf Polycomb group (PcG)
gptkbp:foundIn gptkb:Homo_sapiens
gptkb:Drosophila_melanogaster
gptkbp:function transcriptional activation
epigenetic regulation
https://www.w3.org/2000/01/rdf-schema#label Trithorax group (TrxG)
gptkbp:mutationAssociatedWith homeotic transformations
gptkbp:orthologIn mammals
plants
gptkbp:regulates gptkb:Hox_genes
gene expression memory
gptkbp:relatedTo cell identity maintenance
developmental gene regulation
gptkbp:bfsParent gptkb:Trithorax-group_proteins
gptkbp:bfsLayer 8