|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:HRX
ALL-1
TRX2
Myeloid/lymphoid or mixed-lineage leukemia protein 1
|
|
gptkbp:amendedBy
|
histone H3 lysine 4 (H3K4)
|
|
gptkbp:associatedWith
|
gptkb:leukemia
gptkb:acute_myeloid_leukemia
|
|
gptkbp:domain
|
SET domain
CXXC domain
FYRC domain
FYRN domain
PHD finger
AT hook
|
|
gptkbp:Entrez_Gene_ID
|
4297
|
|
gptkbp:enzymeCommissionNumber
|
2.1.1.354
|
|
gptkbp:expressedIn
|
gptkb:nucleus
|
|
gptkbp:formsFusionGeneWith
|
gptkb:ENL
gptkb:CBP
gptkb:ELL
AF4
AF10
AF6
AF9
Septin 6
|
|
gptkbp:fullName
|
Mixed-lineage leukemia protein 1
|
|
gptkbp:function
|
regulation of gene expression
histone methyltransferase
|
|
gptkbp:gene
|
gptkb:KMT2A
MLL
|
|
gptkbp:HGNC_ID
|
7132
|
|
gptkbp:interactsWith
|
gptkb:ASH2L
gptkb:DPY30
gptkb:RBBP5
gptkb:WDR5
gptkb:MEN1
|
|
gptkbp:involvedIn
|
embryonic development
hematopoiesis
transcriptional regulation
|
|
gptkbp:locatedOnChromosome
|
gptkb:11q23
chromosome 11
|
|
gptkbp:mutationAssociatedWith
|
gptkb:leukemia
gptkb:point_mutation
translocation
deletion
|
|
gptkbp:OMIM
|
159555
|
|
gptkbp:orthologInMouse
|
Mll1
|
|
gptkbp:UniProtID
|
Q03164
|
|
gptkbp:bfsParent
|
gptkb:ASH2L
gptkb:RBBP5
gptkb:WDR5
gptkb:Trithorax-group_(TrxG)_protein_family
gptkb:Trithorax-group_proteins
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MLL1
|