Statements (101)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
homeobox genes |
| gptkbp:arranged_in |
clusters
|
| gptkbp:clusters_in_mammals |
gptkb:HOXA
gptkb:HOXB gptkb:HOXC gptkb:HOXD |
| gptkbp:compatibleWith |
fungi
plants |
| gptkbp:contains |
homeobox domain
|
| gptkbp:discoveredBy |
gptkb:Drosophila_melanogaster
|
| gptkbp:encodes |
transcription factors
|
| gptkbp:evolutionary_conserved |
yes
|
| gptkbp:expressed_during |
embryonic development
|
| gptkbp:expression_pattern |
colinear with chromosomal arrangement
|
| gptkbp:firstDescribed |
gptkb:Edward_B._Lewis
|
| gptkbp:foundIn |
animals
|
| gptkbp:function |
regulate body plan along anterior-posterior axis
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hox genes
|
| gptkbp:influenced |
organogenesis
craniofacial development neural development segment identity urogenital system development limb development patterning of limbs digestive tract development patterning of abdomen patterning of antennae patterning of appendages patterning of arms in cephalopods patterning of beak in cephalopods patterning of central nervous system patterning of chromatophores patterning of digits patterning of ears patterning of eyes patterning of feathers patterning of fins patterning of fins in cephalopods patterning of foot in mollusks patterning of gills patterning of gonads patterning of gut patterning of hair patterning of halteres in flies patterning of heart patterning of hindbrain patterning of ink sac patterning of kidneys patterning of labium patterning of lateral line patterning of legs patterning of lungs patterning of mandibles patterning of mantle patterning of maxillae patterning of mouthparts patterning of operculum patterning of pharyngeal arches patterning of proboscis patterning of radula patterning of ribs patterning of scales patterning of scales in fish patterning of shell in mollusks patterning of siphon patterning of skin patterning of somites patterning of spinal cord patterning of suckers in cephalopods patterning of swim bladder patterning of tail patterning of teeth patterning of tentacles patterning of thorax patterning of vertebrae patterning of wings patterning of wings in insects reproductive tract development vertebral identity |
| gptkbp:locatedOn |
different chromosomes in mammals
|
| gptkbp:mutationAssociatedWith |
homeotic transformations
|
| gptkbp:Nobel_Prize_awarded_to |
gptkb:Christiane_Nüsslein-Volhard
gptkb:Edward_B._Lewis gptkb:Eric_Wieschaus |
| gptkbp:Nobel_Prize_related_to |
gptkb:1995_Nobel_Prize_in_Physiology_or_Medicine
|
| gptkbp:number_of_clusters_in_mammals |
four
|
| gptkbp:orthologIn |
many animal phyla
|
| gptkbp:presentIn |
invertebrates
vertebrates |
| gptkbp:regulates |
downstream target genes
|
| gptkbp:relatedTo |
gptkb:ParaHox_genes
gptkb:NK_genes |
| gptkbp:studiedBy |
evolutionary developmental biology
|
| gptkbp:bfsParent |
gptkb:Antp
gptkb:Hox_gene_complex gptkb:Polycomb-group_proteins gptkb:Ubx gptkb:PREP1 |
| gptkbp:bfsLayer |
7
|