Triggering receptor expressed on myeloid cells 2

URI: https://gptkb.org/entity/Triggering_receptor_expressed_on_myeloid_cells_2
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation gptkb:TREM2
gptkbp:alternativeName TREM-2
Triggering receptor expressed on monocytes 2
Triggering receptor expressed on myeloid cells-like transcript 2
gptkbp:associatedWith gptkb:Alzheimer's_disease
gptkb:Nasu-Hakola_disease
frontotemporal dementia
gptkbp:biologicalProcess receptor activity
innate immune response
regulation of cytokine production
microglial activation
gptkbp:Entrez_Gene_ID gptkb:ENSG00000095970
54209
gptkbp:expressed_in_cell_type gptkb:microglia
myeloid cells
gptkbp:foundIn gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:function regulation of phagocytosis
immune receptor
modulation of inflammation
gptkbp:gene gptkb:TREM2
gptkb:TREM2_gene
gptkbp:HGNC_ID 17761
https://www.w3.org/2000/01/rdf-schema#label Triggering receptor expressed on myeloid cells 2
gptkbp:interactsWith gptkb:DAP12
gptkbp:locatedOnChromosome gptkb:6p21.1
gptkbp:location gptkb:cell_membrane
gptkbp:OMIM 605086
gptkbp:proteinFamily gptkb:immunoglobulin_superfamily
gptkbp:UniProtID gptkb:Q9NZC2
gptkbp:bfsParent gptkb:TREM2
gptkbp:bfsLayer 7