|
gptkbp:instanceOf
|
gptkb:chemical_compound
antidepressant
monoamine oxidase inhibitor
|
|
gptkbp:approvedBy
|
1961
|
|
gptkbp:ATCCode
|
N06AF04
|
|
gptkbp:brand
|
gptkb:Parnate
|
|
gptkbp:CASNumber
|
13492-01-8
|
|
gptkbp:category
|
amphetamine
cyclopropane derivative
|
|
gptkbp:contraindication
|
gptkb:pheochromocytoma
cerebrovascular disease
severe cardiovascular disease
|
|
gptkbp:discoveredBy
|
gptkb:Smith,_Kline_&_French
|
|
gptkbp:drugInteraction
|
gptkb:SSRIs
gptkb:TCAs
gptkb:sympathomimetics
tyramine-containing foods
|
|
gptkbp:eliminationHalfLife
|
1.5 to 3 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:hasMolecularFormula
|
C9H11N
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Tranylcypromine
|
|
gptkbp:IUPACName
|
gptkb:(±)-trans-2-phenylcyclopropan-1-amine
|
|
gptkbp:KEGGID
|
D08668
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
irreversible inhibitor of monoamine oxidase
|
|
gptkbp:MeSH_ID
|
gptkb:D014244
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
133.19 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1082
gptkb:DB00752
15770
16623
|
|
gptkbp:riskFactor
|
gptkb:serotonin_syndrome
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
dizziness
insomnia
dry mouth
hypertensive crisis
|
|
gptkbp:synonym
|
gptkb:Parnate
gptkb:trans-2-phenylcyclopropylamine
|
|
gptkbp:UNII
|
620X0222FQ
|
|
gptkbp:usedFor
|
gptkb:major_depressive_disorder
treatment-resistant depression
|
|
gptkbp:bfsParent
|
gptkb:Antidepressants
|
|
gptkbp:bfsLayer
|
6
|