T follicular helper cells

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf immune response
gptkbp:differentiation_regulated_by gptkb:IL-6
Bcl6
IL-21
gptkbp:expressedIn gptkb:CXCR5
gptkb:ICOS
gptkb:PD-1
Bcl6
gptkbp:firstDescribed 2000
gptkbp:function help B cells produce antibodies
promote germinal center formation
support affinity maturation
support class switch recombination
https://www.w3.org/2000/01/rdf-schema#label T follicular helper cells
gptkbp:identified_in secondary lymphoid organs
gptkbp:interactsWith gptkb:B_cells
gptkb:follicular_dendritic_cells
gptkbp:location germinal center
gptkbp:marking gptkb:CXCR5
gptkb:ICOS
gptkb:PD-1
Bcl6
gptkbp:role leukemia
immunodeficiency
autoimmunity
gptkbp:secretes gptkb:IL-4
IL-21
gptkbp:species gptkb:human
gptkb:mouse
gptkbp:subclassOf gptkb:CD4+_T_cell
gptkbp:bfsParent gptkb:CXCR5
gptkb:Tfh_cells
gptkbp:bfsLayer 7