|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:PML
|
|
gptkbp:associatedWith
|
gptkb:acute_promyelocytic_leukemia
|
|
gptkbp:discoveredBy
|
Pier Giuseppe Pelicci
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:domain
|
RING finger domain
coiled-coil domain
nuclear localization signal
B-box type 1
B-box type 2
|
|
gptkbp:encodedBy
|
TRIM19 gene
|
|
gptkbp:Entrez_Gene_ID
|
5371
ENSG00000140464
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:formsFusionGeneWith
|
gptkb:RARA
|
|
gptkbp:function
|
tumor suppressor
regulation of apoptosis
regulation of transcription
formation of PML nuclear bodies
|
|
gptkbp:fusionProtein
|
gptkb:PML-RARA
|
|
gptkbp:HGNC_ID
|
9122
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TRIM19
|
|
gptkbp:interactsWith
|
gptkb:SUMO1
gptkb:RB1
gptkb:p53
gptkb:SP100
gptkb:DAXX
|
|
gptkbp:length
|
882
|
|
gptkbp:locatedOnChromosome
|
15q24
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:memberOf
|
gptkb:TRIM_protein_family
|
|
gptkbp:OMIM
|
102578
|
|
gptkbp:orthologInMouse
|
Trim19
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
ubiquitination
|
|
gptkbp:regulates
|
cell proliferation
DNA damage response
antiviral response
cell senescence
|
|
gptkbp:UniProtID
|
P29590
|
|
gptkbp:bfsParent
|
gptkb:TRIM_protein_family
gptkb:Tripartite_motif-containing_protein
gptkb:PML_(gene)
|
|
gptkbp:bfsLayer
|
7
|