|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CD282
Toll/interleukin-1 receptor-like protein 4
TIL4
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
innate immune response
pattern recognition receptors
|
|
gptkbp:discoveredIn
|
1998
|
|
gptkbp:encodes
|
gptkb:Toll-like_receptor_2
|
|
gptkbp:Entrez_Gene_ID
|
7097
ENSG00000137462
|
|
gptkbp:expressedIn
|
dendritic cells
macrophages
monocytes
|
|
gptkbp:foundIn
|
gptkb:cell_membrane
|
|
gptkbp:function
|
activation of NF-kappaB pathway
pattern recognition receptor activity
recognition of bacterial lipoproteins
|
|
gptkbp:GOProcess
|
inflammatory response
immune system process
|
|
gptkbp:HGNC_ID
|
11848
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TLR2 gene
|
|
gptkbp:interactsWith
|
gptkb:CD14
MyD88
MAL/TIRAP
TLR1 protein
TLR6 protein
|
|
gptkbp:length
|
2 exons
784 amino acids
|
|
gptkbp:locatedOnChromosome
|
4
4q31.3
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Crohn's_disease
asthma
sepsis
tuberculosis susceptibility
leprosy susceptibility
|
|
gptkbp:OMIM
|
603028
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Bos_taurus
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:product
|
TLR2 protein
|
|
gptkbp:proteinFamily
|
leucine-rich repeat
TIR domain
|
|
gptkbp:relatedTo
|
gptkb:TLR1_gene
TLR6 gene
|
|
gptkbp:UniProtID
|
O60603
|
|
gptkbp:bfsParent
|
gptkb:TLR2
gptkb:Toll-like_receptor_2
gptkb:CD282
|
|
gptkbp:bfsLayer
|
8
|