Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:BAFF
gptkb:B-cell_activating_factor gptkb:TNFSF13B |
| gptkbp:associatedWith |
autoimmune diseases
|
| gptkbp:binds |
gptkb:TACI
gptkb:BCMA gptkb:BAFF-R |
| gptkbp:discoveredBy |
Genentech researchers
|
| gptkbp:encodedBy |
gptkb:TNFSF13B_gene
|
| gptkbp:expressedIn |
gptkb:B_cells
dendritic cells myeloid cells monocytes |
| gptkbp:function |
stimulates B cell proliferation
promotes B cell survival regulates B cell development |
| https://www.w3.org/2000/01/rdf-schema#label |
TALL-1
|
| gptkbp:involvedIn |
immune response
|
| gptkbp:locatedOnChromosome |
13q32-34
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_ligand_superfamily
|
| gptkbp:molecularWeight |
32 kDa (approximate)
|
| gptkbp:OMIM |
gptkb:603969
|
| gptkbp:overexpressedIn |
gptkb:systemic_lupus_erythematosus
rheumatoid arthritis |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
type II transmembrane protein
|
| gptkbp:UniProtID |
gptkb:Q9Y275
|
| gptkbp:bfsParent |
gptkb:BAFF
|
| gptkbp:bfsLayer |
7
|