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gptkbp:instanceOf
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gptkb:transcription_factor
gptkb:protein
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gptkbp:alternativeName
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Specificity protein 1
TSFP1
Transcription factor Sp1
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gptkbp:associatedWith
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gptkb:Alzheimer's_disease
gptkb:cancer
gptkb:diabetes
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gptkbp:binds
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GC-rich motifs
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gptkbp:discoveredBy
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1983
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gptkbp:DNA_binding_domain
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zinc finger
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gptkbp:expressedIn
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many tissues
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gptkbp:function
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transcriptional activation
regulation of gene expression
DNA binding
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gptkbp:gene
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gptkb:SP1
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gptkbp:interactsWith
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gptkb:CBP/p300
gptkb:TATA-binding_protein
gptkb:HDAC1
gptkb:p53
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gptkbp:locatedOnChromosome
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12q13.1
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gptkbp:location
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gptkb:nucleus
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gptkbp:molecularWeight
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~81 kDa
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:PDB
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1SP1
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gptkbp:postTranslationalModification
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phosphorylation
glycosylation
sumoylation
acetylation
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gptkbp:regulates
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gptkb:immune_response
apoptosis
cell differentiation
DNA repair
metabolism
angiogenesis
cell growth
oncogenes
cell cycle
tumor suppressor genes
cell adhesion
inflammatory response
housekeeping genes
response to oxidative stress
microRNAs
telomerase activity
extracellular matrix genes
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gptkbp:UniProtID
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P08047
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gptkbp:bfsParent
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gptkb:SP1_gene
gptkb:KLF6_protein
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gptkbp:bfsLayer
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8
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https://www.w3.org/2000/01/rdf-schema#label
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Sp1 protein
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