Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:LNK
|
| gptkbp:associatedWith |
autoimmune diseases
myeloproliferative neoplasms |
| gptkbp:encodes |
SH2B adapter protein 3
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000111252
10018 |
| https://www.w3.org/2000/01/rdf-schema#label |
Sh2b3
|
| gptkbp:involvedIn |
hematopoiesis
|
| gptkbp:locatedOnChromosome |
12q24
|
| gptkbp:mutationAssociatedWith |
gptkb:systemic_lupus_erythematosus
essential thrombocythemia celiac disease |
| gptkbp:negativeRegulatorOf |
cytokine signaling
|
| gptkbp:OMIM |
605093
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:proteinFamily |
gptkb:PH_domain
SH2 domain proline-rich region |
| gptkbp:regulates |
gptkb:JAK-STAT_signaling_pathway
T cell activation B cell activation platelet production |
| gptkbp:UniProtID |
gptkb:Q9UQQ2
|
| gptkbp:bfsParent |
gptkb:SH2B3
|
| gptkbp:bfsLayer |
7
|