Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:binds |
gptkb:p53
gptkb:retinoblastoma_protein_(pRb) |
| gptkbp:contains |
ATPase domain
nuclear localization signal DNA binding domain |
| gptkbp:discoveredIn |
gptkb:Simian_Virus_40_(SV40)
|
| gptkbp:encodedBy |
gptkb:SV40_virus
|
| gptkbp:function |
oncogenic transformation
transcriptional regulation viral replication |
| https://www.w3.org/2000/01/rdf-schema#label |
SV40 large T antigen
|
| gptkbp:inhibitedBy |
tumor suppressor proteins
|
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:molecularWeight |
~94 kDa
|
| gptkbp:role |
cell cycle regulation
tumorigenesis DNA replication initiation |
| gptkbp:species |
gptkb:Simian_Virus_40
|
| gptkbp:usedAs |
model for studying oncogenesis
|
| gptkbp:usedIn |
molecular biology research
|
| gptkbp:bfsParent |
gptkb:pRb
gptkb:retinoblastoma-associated_protein |
| gptkbp:bfsLayer |
7
|