Simian Virus 40 (SV40)

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:virus
gptkbp:associatedWith tumor formation in animals
gptkbp:caps gptkb:VP1
gptkb:VP2
gptkb:VP3
gptkbp:controversy possible link to human cancers
gptkbp:discoveredBy gptkb:Maurice_Hilleman
Ben Sweet
gptkbp:discoveredIn 1958
gptkbp:encodes gptkb:Large_T_antigen
Small t antigen
gptkbp:entryReceptor gptkb:MHC_class_I_molecules
gptkbp:genomeSize ~5,243 base pairs
gptkbp:genomeType double-stranded DNA
gptkbp:genus Polyomavirus
gptkbp:hostedBy gptkb:human
gptkb:lion
https://www.w3.org/2000/01/rdf-schema#label Simian Virus 40 (SV40)
gptkbp:notableEvent contaminated early polio vaccines (1955–1963)
gptkbp:oncogenic yes
gptkbp:relatedTo gptkb:JC_virus
BK virus
gptkbp:replicationSite gptkb:nucleus
gptkbp:structure icosahedral
gptkbp:studiedBy cancer research
gptkbp:studiedIn cell transformation
gptkbp:taxonRank gptkb:Polyomaviridae
gptkbp:transmission contaminated polio vaccines
gptkbp:usedAs model for DNA replication
vector in gene therapy research
gptkbp:usedIn molecular biology research
gptkbp:bfsParent gptkb:SV40_large_T_antigen
gptkbp:bfsLayer 8