Statements (53)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
gptkbp:alias |
SRp20
|
gptkbp:alternativeSplicing |
produces multiple isoforms
|
gptkbp:associatedWith |
gptkb:cancer
cell proliferation |
gptkbp:domain |
gptkb:RS_domain
RNA recognition motif (RRM) |
gptkbp:Entrez_Gene_ID |
ENSG00000161547
6428 |
gptkbp:expressedIn |
various human tissues
|
gptkbp:fullName |
Serine/arginine-rich splicing factor 3
|
gptkbp:function |
cell cycle regulation
RNA binding regulation of alternative splicing mRNA export splicing factor |
gptkbp:HGNC_ID |
gptkb:SRSF3
|
https://www.w3.org/2000/01/rdf-schema#label |
SRSF3
|
gptkbp:interactsWith |
other SR proteins
|
gptkbp:length |
164
|
gptkbp:locatedOnChromosome |
gptkb:6p21.31
chr6:36,663,964-36,668,047 |
gptkbp:molecularWeight |
19 kDa
|
gptkbp:OMIM |
600942
|
gptkbp:orthologInMouse |
Srsf3
|
gptkbp:phosphorylates |
SR protein kinases
|
gptkbp:regulates |
apoptosis
cellular senescence alternative splicing of pre-mRNA splicing of Bcl-x splicing of CD44 splicing of FGFR2 splicing of MDM4 splicing of PKM splicing of SRSF1 splicing of SRSF10 splicing of SRSF11 splicing of SRSF12 splicing of SRSF2 splicing of SRSF4 splicing of SRSF5 splicing of SRSF6 splicing of SRSF7 splicing of SRSF8 splicing of SRSF9 splicing of TP53 |
gptkbp:subcellularLocation |
gptkb:nucleus
nucleoplasm nuclear speckles |
gptkbp:UniProtID |
Q13247
|
gptkbp:bfsParent |
gptkb:RRM_domain
|
gptkbp:bfsLayer |
7
|