|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
NEM-sensitive fusion protein
|
|
gptkbp:associatedWith
|
neurodegenerative diseases
neurotransmitter release
membrane trafficking
|
|
gptkbp:discoveredBy
|
gptkb:James_E._Rothman
|
|
gptkbp:discoveredIn
|
1988
|
|
gptkbp:EC_number
|
3.6.4.6
|
|
gptkbp:encodedBy
|
gptkb:NSF_gene
|
|
gptkbp:fullName
|
N-ethylmaleimide-sensitive factor
|
|
gptkbp:function
|
ATP binding
SNARE binding
ATPase involved in vesicle fusion
disassembles SNARE complexes
|
|
gptkbp:GOProcess
|
vesicle-mediated transport
synaptic vesicle exocytosis
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NSF protein
|
|
gptkbp:interactsWith
|
gptkb:SNARE_proteins
gptkb:SNAP_proteins
|
|
gptkbp:locatedOnChromosome
|
17q21.31
|
|
gptkbp:location
|
gptkb:cell_membrane
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
~82 kDa
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Saccharomyces_cerevisiae
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
1NSF
|
|
gptkbp:structure
|
hexamer
|
|
gptkbp:UniProtID
|
gptkb:P46459
|
|
gptkbp:bfsParent
|
gptkb:soluble_NSF_attachment_protein_receptor_(SNARE)_family
gptkb:SNARE_proteins
|
|
gptkbp:bfsLayer
|
7
|