|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:autism_spectrum_disorder
epilepsy
neurodevelopmental disorders
|
|
gptkbp:binds
|
gptkb:calcium_ion
phospholipid membrane
|
|
gptkbp:discoveredBy
|
gptkb:Thomas_C._Südhof
|
|
gptkbp:domain
|
C2 domain
|
|
gptkbp:function
|
regulation of neurotransmitter release
calcium sensor
|
|
gptkbp:gene_location_(human)
|
chromosome 12q21.2 (SYT1)
|
|
gptkbp:hasMember
|
synaptotagmin-1
synaptotagmin-2
synaptotagmin-7
synaptotagmin-9
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
synaptotagmin
|
|
gptkbp:interactsWith
|
gptkb:SNAP-25
gptkb:SNARE_complex
gptkb:syntaxin
gptkb:synaptobrevin
|
|
gptkbp:involves
|
synaptic vesicle fusion
|
|
gptkbp:location
|
synaptic vesicle membrane
|
|
gptkbp:molecularWeight
|
~65 kDa (for synaptotagmin-1)
|
|
gptkbp:organism
|
gptkb:human
gptkb:mouse
gptkb:Drosophila_melanogaster
|
|
gptkbp:proteinFamily
|
gptkb:SYT
|
|
gptkbp:relatedTo
|
synaptic transmission
exocytosis
|
|
gptkbp:bfsParent
|
gptkb:SNAP-25
gptkb:synaptic_vesicle
gptkb:SNARE_proteins
|
|
gptkbp:bfsLayer
|
7
|