Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:autism_spectrum_disorder
epilepsy neurodevelopmental disorders |
| gptkbp:binds |
gptkb:calcium_ion
phospholipid membrane |
| gptkbp:discoveredBy |
gptkb:Thomas_C._Südhof
|
| gptkbp:domain |
C2 domain
|
| gptkbp:function |
regulation of neurotransmitter release
calcium sensor |
| gptkbp:gene_location_(human) |
chromosome 12q21.2 (SYT1)
|
| gptkbp:hasMember |
synaptotagmin-1
synaptotagmin-2 synaptotagmin-7 synaptotagmin-9 |
| gptkbp:interactsWith |
gptkb:SNAP-25
gptkb:SNARE_complex gptkb:syntaxin gptkb:synaptobrevin |
| gptkbp:involves |
synaptic vesicle fusion
|
| gptkbp:location |
synaptic vesicle membrane
|
| gptkbp:molecularWeight |
~65 kDa (for synaptotagmin-1)
|
| gptkbp:organism |
gptkb:human
gptkb:mouse gptkb:Drosophila_melanogaster |
| gptkbp:proteinFamily |
gptkb:SYT
|
| gptkbp:relatedTo |
synaptic transmission
exocytosis |
| gptkbp:bfsParent |
gptkb:SNAP-25
gptkb:SNARE_proteins |
| gptkbp:bfsLayer |
7
|
| http://www.w3.org/2000/01/rdf-schema#label |
synaptotagmin
|