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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alternativeName
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SMAD specific E3 ubiquitin protein ligase 2
SMAD ubiquitination regulatory factor 2
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gptkbp:associatedWith
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gptkb:cancer
fibrosis
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gptkbp:biologicalProcess
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gptkb:TGF-beta_signaling_pathway
protein ubiquitination
ubiquitin-protein transferase activity
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gptkbp:cellularComponent
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gptkb:nucleus
gptkb:cytoplasm
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gptkbp:domain
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gptkb:WW_domain
gptkb:HECT_domain
C2 domain
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gptkbp:encodedBy
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SMURF2 gene
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gptkbp:function
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gptkb:E3_ubiquitin-protein_ligase
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https://www.w3.org/2000/01/rdf-schema#label
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SMURF2 protein
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gptkbp:interactsWith
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gptkb:SMURF1_protein
SMAD2 protein
SMAD7 protein
RNF20 protein
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gptkbp:length
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748 amino acids
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gptkbp:locatedOnChromosome
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gptkb:17q23.3
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:postTranslationalModification
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phosphorylation
ubiquitination
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gptkbp:regulates
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cell proliferation
cellular senescence
cell cycle
TGF-beta receptor degradation
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gptkbp:UniProtID
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Q9HAU4
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gptkbp:bfsParent
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gptkb:WW_domain
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gptkbp:bfsLayer
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7
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