|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:OCT1
solute carrier family 22 member 1
|
|
gptkbp:associatedWith
|
gptkb:type_2_diabetes
drug response
metformin pharmacokinetics
|
|
gptkbp:discoveredBy
|
Koepsell et al.
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
gptkb:OCT1
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000183023
6580
|
|
gptkbp:expressedIn
|
gptkb:kidney
liver
intestine
|
|
gptkbp:fullName
|
solute carrier family 22 member 1
|
|
gptkbp:function
|
organic cation transporter
|
|
gptkbp:gene
|
gptkb:SLC22A1
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
NM_003057
|
|
gptkbp:HGNC_ID
|
10963
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SLC22A1
|
|
gptkbp:length
|
554 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
6q25.3
|
|
gptkbp:memberOf
|
gptkb:solute_carrier_family
organic cation transporter family
|
|
gptkbp:molecularWeight
|
61 kDa
|
|
gptkbp:mutationAssociatedWith
|
drug transport
metformin efficacy
|
|
gptkbp:OMIM
|
602607
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Slc22a1
|
|
gptkbp:product
|
gptkb:OCT1
|
|
gptkbp:transportation
|
gptkb:metformin
gptkb:choline
gptkb:histamine
gptkb:tetraethylammonium
dopamine
serotonin
|
|
gptkbp:UniProtID
|
O15245
|
|
gptkbp:bfsParent
|
gptkb:solute_carrier_family
|
|
gptkbp:bfsLayer
|
6
|