Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
gptkb:Signal-regulatory_protein_alpha
CD172a SHPS-1 |
| gptkbp:binds |
gptkb:CD47
|
| gptkbp:domain |
ITIM motif
immunoglobulin domain |
| gptkbp:encodedBy |
SIRPA gene
|
| gptkbp:Entrez_Gene_ID |
6610
|
| gptkbp:expressedIn |
neurons
myeloid cells |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
cell surface receptor
regulation of immune response |
| gptkbp:HGNC_ID |
HGNC:10418
|
| https://www.w3.org/2000/01/rdf-schema#label |
SIRP alpha
|
| gptkbp:inhibitedBy |
macrophage activation
|
| gptkbp:interactsWith |
protein tyrosine phosphatases SHP-1
protein tyrosine phosphatases SHP-2 |
| gptkbp:locatedOnChromosome |
chromosome 20p13
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:memberOf |
SIRP family
|
| gptkbp:OMIM |
601734
|
| gptkbp:PDB |
2JJS
|
| gptkbp:regulates |
phagocytosis
|
| gptkbp:role |
immunotherapy
cancer immunotherapy research |
| gptkbp:UniProtID |
gptkb:P78324
|
| gptkbp:bfsParent |
gptkb:SIRPA
|
| gptkbp:bfsLayer |
7
|