|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:S100A9
gptkb:calgranulin_B
|
|
gptkbp:associatedWith
|
gptkb:cancer
psoriasis
cystic fibrosis
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:encodedBy
|
S100A9 gene
|
|
gptkbp:Entrez_Gene_ID
|
6280
|
|
gptkbp:expressedIn
|
myeloid cells
|
|
gptkbp:formsComplexWith
|
MRP8
calprotectin
|
|
gptkbp:foundIn
|
monocytes
neutrophils
|
|
gptkbp:function
|
antimicrobial activity
chelation of divalent metal ions
regulation of inflammatory processes
|
|
gptkbp:hasBiomarker
|
inflammatory diseases
rheumatoid arthritis
inflammatory bowel disease
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MRP14
|
|
gptkbp:interactsWith
|
gptkb:TLR4
gptkb:RAGE
|
|
gptkbp:involvedIn
|
inflammatory response
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q21
|
|
gptkbp:memberOf
|
gptkb:S100_protein_family
|
|
gptkbp:molecularWeight
|
13 kDa
|
|
gptkbp:OMIM
|
123885
|
|
gptkbp:orthologInMouse
|
S100a9
|
|
gptkbp:PDB
|
1IRJ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
oxidation
|
|
gptkbp:regulates
|
cytoskeleton dynamics
leukocyte migration
NADPH oxidase activity
|
|
gptkbp:structure
|
EF-hand calcium-binding protein
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
extracellular space
|
|
gptkbp:UniProtID
|
P06702
|
|
gptkbp:bfsParent
|
gptkb:CGRN
|
|
gptkbp:bfsLayer
|
6
|