RhoGDI1

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName GDIA
Rho GDP dissociation inhibitor alpha
Rho GDI alpha
gptkbp:associatedWith nephrotic syndrome
gptkbp:biologicalProcess cell migration
cytoskeleton organization
regulation of small GTPase mediated signal transduction
gptkbp:encodedBy ARHGDIA gene
gptkbp:Entrez_Gene_ID ENSG00000132016
gptkbp:fullName Rho GDP-dissociation inhibitor 1
gptkbp:function regulates Rho family GTPases
inhibits GDP dissociation from Rho GTPases
gptkbp:gene gptkb:ARHGDIA
gptkbp:HGNC_ID 672
https://www.w3.org/2000/01/rdf-schema#label RhoGDI1
gptkbp:interactsWith gptkb:RhoA
gptkb:Rac1
gptkb:Cdc42
gptkbp:length 204 amino acids
gptkbp:locatedOnChromosome gptkb:17q25
gptkbp:location gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:molecularWeight 23 kDa
gptkbp:OMIM 601925
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 1RHO
gptkbp:RefSeq NM_004309
gptkbp:structure contains a RhoGDI domain
gptkbp:tissue_specificity ubiquitous
gptkbp:UniProtID P52565
gptkbp:bfsParent gptkb:RhoGDI
gptkbp:bfsLayer 7