|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:RhoGDI1
GDIA
Rho GDP dissociation inhibitor alpha
|
|
gptkbp:associatedWith
|
nephrotic syndrome
|
|
gptkbp:biologicalProcess
|
regulation of small GTPase mediated signal transduction
GTPase regulator activity
|
|
gptkbp:cellularComponent
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:chromosomeArm
|
gptkb:17q25
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:encodes
|
Rho GDP-dissociation inhibitor 1
|
|
gptkbp:Entrez_Gene_ID
|
396
ENSG00000161970
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
regulation of Rho GTPases
inhibition of GDP dissociation from Rho proteins
|
|
gptkbp:HGNC_ID
|
HGNC:672
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ARHGDIA
|
|
gptkbp:interactsWith
|
gptkb:CDC42
gptkb:RHOA
gptkb:RAC1
|
|
gptkbp:length
|
204 amino acids
|
|
gptkbp:locatedOnChromosome
|
17
|
|
gptkbp:mutationAssociatedWith
|
nephrotic syndrome type 8
|
|
gptkbp:OMIM
|
601924
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Arhgdia
|
|
gptkbp:product
|
RhoGDI alpha
|
|
gptkbp:RefSeq
|
NM_001198915
|
|
gptkbp:UniProtID
|
P52565
|
|
gptkbp:bfsParent
|
gptkb:CDC42
gptkb:Ras_homolog_family_member_A
gptkb:RhoGDI
|
|
gptkbp:bfsLayer
|
7
|