Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:affects |
hematopoiesis
myeloid differentiation |
| gptkbp:alsoKnownAs |
gptkb:AML1-ETO
RUNX1/ETO |
| gptkbp:associatedWith |
gptkb:acute_myeloid_leukemia
|
| gptkbp:chromosomalTranslocation |
gptkb:t(8;21)(q22;q22)
|
| gptkbp:detects |
gptkb:FISH
gptkb:RT-PCR |
| gptkbp:disrupts |
normal gene regulation
|
| gptkbp:encodes |
chimeric transcription factor
|
| gptkbp:Entrez_Gene_ID |
861
|
| gptkbp:firstDescribed |
1993
|
| gptkbp:foundIn |
gptkb:human
|
| gptkbp:hasBiomarker |
gptkb:acute_myeloid_leukemia
|
| gptkbp:HGNC_ID |
10471
|
| https://www.w3.org/2000/01/rdf-schema#label |
RUNX1-RUNX1T1
|
| gptkbp:involves |
leukemogenesis
|
| gptkbp:locatedOnChromosome |
chromosome 21
chromosome 8 |
| gptkbp:mergedInto |
gptkb:RUNX1
RUNX1T1 |
| gptkbp:OMIM |
151385
|
| gptkbp:target |
targeted therapies in AML
|
| gptkbp:UniProtID |
Q01196
|
| gptkbp:bfsParent |
gptkb:t(8;21)_translocation
|
| gptkbp:bfsLayer |
6
|