Statements (19)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:affectsProcess |
hematopoiesis
|
| gptkbp:alsoKnownAs |
RUNX1-RUNX1T1 fusion protein
|
| gptkbp:altersFunctionOf |
transcription regulation
|
| gptkbp:associatedWith |
gptkb:acute_myeloid_leukemia
|
| gptkbp:detects |
gptkb:FISH
gptkb:RT-PCR |
| gptkbp:disrupts |
normal differentiation of myeloid cells
|
| gptkbp:firstDescribed |
1992
|
| gptkbp:formedBy |
t(8;21)(q22;q22) chromosomal translocation
|
| https://www.w3.org/2000/01/rdf-schema#label |
AML1-ETO
|
| gptkbp:involvedIn |
gptkb:RUNX1
RUNX1T1 |
| gptkbp:proteinFamily |
Runt domain
NHR domains |
| gptkbp:target |
therapeutic research in leukemia
|
| gptkbp:usedAs |
diagnostic marker in AML
|
| gptkbp:bfsParent |
gptkb:t(8;21)_translocation
|
| gptkbp:bfsLayer |
6
|