Statements (29)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alias |
gptkb:RING_finger_protein_8
gptkb:hRNF8 |
gptkbp:associatedWith |
gptkb:cancer
genomic stability |
gptkbp:discoveredIn |
2003
|
gptkbp:encodes |
gptkb:E3_ubiquitin-protein_ligase_RNF8
|
gptkbp:Entrez_Gene_ID |
51474
ENSG00000189058 |
gptkbp:function |
DNA damage response
ubiquitin-protein transferase activity |
gptkbp:HGNC_ID |
HGNC:18667
|
https://www.w3.org/2000/01/rdf-schema#label |
RNF8
|
gptkbp:interactsWith |
gptkb:UBC13
gptkb:53BP1 gptkb:MDC1 gptkb:RNF168 |
gptkbp:locatedOnChromosome |
gptkb:chromosome_6
|
gptkbp:location |
gptkb:nucleus
|
gptkbp:OMIM |
610333
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:orthologInMouse |
gptkb:Rnf8
|
gptkbp:proteinFamily |
RING finger domain
FHA domain |
gptkbp:regulates |
DNA double-strand break repair
histone ubiquitination |
gptkbp:UniProtID |
Q9NYZ3
|
gptkbp:bfsParent |
gptkb:HERC2
|
gptkbp:bfsLayer |
7
|