|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:NORE1
gptkb:NORE1A
gptkb:RAPL
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
hepatocellular carcinoma
epigenetic silencing
|
|
gptkbp:biologicalProcess
|
signal transduction
apoptotic process
cell cycle arrest
protein binding
GTPase binding
|
|
gptkbp:discoveredBy
|
Tommaso F. et al.
|
|
gptkbp:domain
|
Ras-association domain
SARAH domain
|
|
gptkbp:encodes
|
gptkb:Ras_association_domain-containing_protein_5
|
|
gptkbp:Entrez_Gene_ID
|
83593
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:firstDescribed
|
2000
|
|
gptkbp:fullName
|
gptkb:Ras_association_domain-containing_protein_5
|
|
gptkbp:function
|
tumor suppressor
cell cycle regulation
regulation of apoptosis
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:16857
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RASSF5
|
|
gptkbp:interactsWith
|
gptkb:Ras_proteins
gptkb:MST1
gptkb:MOAP1
gptkb:MST2
gptkb:PAR-4
|
|
gptkbp:length
|
418
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
|
|
gptkbp:methylationAssociatedWith
|
gene silencing
|
|
gptkbp:mutationAssociatedWith
|
tumorigenesis
|
|
gptkbp:OMIM
|
605082
|
|
gptkbp:orthologInMouse
|
gptkb:Rassf5
|
|
gptkbp:regulates
|
gptkb:Hippo_signaling_pathway
apoptosis
cell proliferation
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
Q8WWW0
|
|
gptkbp:bfsParent
|
gptkb:RAP2A
gptkb:P01116
gptkb:3265_(HRAS)
gptkb:KEGG:_hsa04014
gptkb:P01112_(HRAS)
|
|
gptkbp:bfsLayer
|
6
|