|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:EPAC2
gptkb:cAMP-regulated_guanine_nucleotide_exchange_factor_II
|
|
gptkbp:associatedWith
|
insulin secretion
neuronal signaling
|
|
gptkbp:chromosome_location_(mouse)
|
chromosome 1
|
|
gptkbp:encodes
|
gptkb:Rap_guanine_nucleotide_exchange_factor_4
|
|
gptkbp:Ensembl_ID_(human)
|
ENSG00000115935
|
|
gptkbp:Ensembl_ID_(mouse)
|
ENSMUSG00000026077
|
|
gptkbp:expressedIn
|
brain
pancreas
|
|
gptkbp:function
|
acts as a guanine nucleotide exchange factor for Rap1 and Rap2
mediates cAMP signaling
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rapgef4
|
|
gptkbp:locatedOnChromosome
|
chromosome 2q31.1
|
|
gptkbp:mutationAssociatedWith
|
neurodevelopmental disorders
|
|
gptkbp:NCBI_Gene_ID_(human)
|
11069
|
|
gptkbp:NCBI_Gene_ID_(mouse)
|
56406
|
|
gptkbp:OMIM
|
605197
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:zebrafish
right
|
|
gptkbp:proteinFamily
|
Ras-GEF domain
cAMP-binding domain
cAMP-binding proteins
|
|
gptkbp:UniProtID
|
Q8WZA2
|
|
gptkbp:bfsParent
|
gptkb:RAPGEF4
|
|
gptkbp:bfsLayer
|
7
|