Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
gptkb:RAF_proto-oncogene_serine/threonine-protein_kinase
c-RAF protein |
gptkbp:encodedBy |
RAF1A gene
|
gptkbp:foundIn |
gptkb:Homo_sapiens
|
gptkbp:function |
serine/threonine-protein kinase activity
|
https://www.w3.org/2000/01/rdf-schema#label |
RAF1A protein
|
gptkbp:interactsWith |
gptkb:RAS_protein
gptkb:14-3-3_protein gptkb:MEK1_protein |
gptkbp:involvedIn |
gptkb:MAPK/ERK_signaling_pathway
|
gptkbp:location |
gptkb:cytoplasm
mitochondrion |
gptkbp:molecularWeight |
approximately 74 kDa
|
gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:Noonan_syndrome |
gptkbp:phosphorylates |
Ser338
Tyr341 |
gptkbp:regulates |
apoptosis
cell differentiation cell proliferation |
gptkbp:bfsParent |
gptkb:raf1a
|
gptkbp:bfsLayer |
7
|