Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:MAP2K1
gptkb:Mitogen-activated_protein_kinase_kinase_1 |
| gptkbp:encodedBy |
gptkb:MAP2K1_gene
|
| gptkbp:function |
serine/threonine kinase
phosphorylates ERK1/2 |
| https://www.w3.org/2000/01/rdf-schema#label |
MEK1 protein
|
| gptkbp:inhibitedBy |
gptkb:trametinib
gptkb:cobimetinib |
| gptkbp:involvedIn |
gptkb:MAPK/ERK_signaling_pathway
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
approximately 43 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:Noonan_syndrome |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:phosphorylates |
RAF kinases
|
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:UniProtID |
Q02750
|
| gptkbp:bfsParent |
gptkb:MAP2K1_gene
|
| gptkbp:bfsLayer |
7
|