Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:associatedWith |
meiosis
mitosis chromosome segregation |
| gptkbp:biologicalProcess |
cysteine endopeptidase activity
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:EC_number |
3.4.22.49
|
| gptkbp:encodedBy |
gptkb:ESPL1_gene
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
cleaves cohesin complex
|
| gptkbp:involvedIn |
cell division
anaphase |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:orthologIn |
gptkb:human_ESPL1
gptkb:yeast_Esp1 |
| gptkbp:regulates |
activated by APC/C
inhibited by securin |
| gptkbp:role |
separates sister chromatids
|
| gptkbp:bfsParent |
gptkb:RAD21
|
| gptkbp:bfsLayer |
6
|
| https://www.w3.org/2000/01/rdf-schema#label |
Separase
|