Pre-B-cell leukemia homeobox 1

URI: https://gptkb.org/entity/Pre-B-cell_leukemia_homeobox_1
GPTKB entity
Statements (35)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alias gptkb:OTTHUMP00000021264
gptkb:PBX1A
gptkb:PRL
gptkbp:alternativeSplicing yes
gptkbp:associatedWith gptkb:pre-B-cell_acute_lymphoblastic_leukemia
leukemia
congenital anomalies of the kidney and urinary tract
gptkbp:biologicalProcess transcription regulation
sequence-specific DNA binding
gptkbp:encodedBy gptkb:PBX1_gene
gptkbp:Entrez_Gene_ID 5087
ENSG00000115155
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function transcription factor
regulation of gene expression
DNA binding
gptkbp:HGNC_ID HGNC:8635
https://www.w3.org/2000/01/rdf-schema#label Pre-B-cell leukemia homeobox 1
gptkbp:interactsWith gptkb:PBX2
gptkb:PBX3
gptkb:HOX_proteins
gptkb:MEIS1
gptkbp:locatedOnChromosome gptkb:chromosome_1q23
gptkbp:mutationAssociatedWith oncogenic fusion with E2A in leukemia
gptkbp:OMIM 176265
gptkbp:orthologIn gptkb:mouse_Pbx1
gptkbp:proteinFamily gptkb:TALE_class_homeobox_genes
homeobox genes
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:symbol gptkb:PBX1
gptkbp:UniProtID P40424
gptkbp:bfsParent gptkb:PBX1
gptkbp:bfsLayer 6