Polycomb group protein complex
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:amendedBy |
histone H2A lysine 119
histone H3 lysine 27 |
| gptkbp:associatedWith |
histone methylation
histone ubiquitination |
| gptkbp:component |
epigenetic regulation
|
| gptkbp:contains |
gptkb:Polycomb_repressive_complex_1
gptkb:Polycomb_repressive_complex_2 |
| gptkbp:discoveredIn |
gptkb:Drosophila_melanogaster
|
| gptkbp:enemyOf |
Trithorax group protein complex
|
| gptkbp:firstDescribed |
1978
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
gene silencing
chromatin modification |
| https://www.w3.org/2000/01/rdf-schema#label |
Polycomb group protein complex
|
| gptkbp:involvedIn |
cell identity maintenance
developmental gene regulation |
| gptkbp:involves |
gptkb:cancer
gptkb:X-chromosome_inactivation stem cell pluripotency |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:namedAfter |
gptkb:Polycomb_gene
|
| gptkbp:regulates |
gptkb:Hox_genes
|
| gptkbp:subunit |
gptkb:EED
gptkb:EZH2 gptkb:CBX_proteins gptkb:PHC_proteins gptkb:RING1A gptkb:RING1B gptkb:SUZ12 BMI1 |
| gptkbp:bfsParent |
gptkb:PcG
|
| gptkbp:bfsLayer |
8
|