Polycomb repressive complex 1
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:PRC1
|
| gptkbp:catalyzes |
monoubiquitination of histone H2A at lysine 119
|
| gptkbp:component |
gptkb:KDM2B
gptkb:CBX_proteins gptkb:PHC_proteins gptkb:RING1A gptkb:RING1B BMI1 RYBP |
| gptkbp:discoveredBy |
gptkb:Drosophila_melanogaster
|
| gptkbp:function |
gene silencing
chromatin modification |
| https://www.w3.org/2000/01/rdf-schema#label |
Polycomb repressive complex 1
|
| gptkbp:involves |
cancer progression
stem cell maintenance epigenetic regulation developmental gene regulation |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:mechanismOfAction |
transcriptional repression
chromatin compaction |
| gptkbp:part_of |
gptkb:Polycomb_group_proteins
|
| gptkbp:regulates |
gptkb:HOX_genes
cell cycle genes differentiation genes |
| gptkbp:relatedTo |
gptkb:Polycomb_repressive_complex_2
|
| gptkbp:bfsParent |
gptkb:ANRIL
|
| gptkbp:bfsLayer |
7
|