Trithorax group (TrxG) pathway
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:amendedBy |
histones
|
| gptkbp:catalyzes |
H3K4 methylation
|
| gptkbp:conservedIn |
animals
|
| gptkbp:countermeasures |
gene silencing
|
| gptkbp:enemyOf |
gptkb:Polycomb_group_(PcG)_pathway
|
| gptkbp:firstDescribed |
gptkb:Drosophila_melanogaster
|
| https://www.w3.org/2000/01/rdf-schema#label |
Trithorax group (TrxG) pathway
|
| gptkbp:importantFor |
development
cell identity |
| gptkbp:includes |
gptkb:MLL_complex
chromatin remodeling complexes ASH1L histone methyltransferases SET1A SET1B |
| gptkbp:involves |
gptkb:Trithorax_group_proteins
epigenetic regulation |
| gptkbp:maintainedBy |
active chromatin state
|
| gptkbp:regulates |
gptkb:HOX_genes
gene expression |
| gptkbp:bfsParent |
gptkb:Polycomb_group_(PcG)_pathway
|
| gptkbp:bfsLayer |
8
|