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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alternativeName
|
gptkb:E(z)_protein
gptkb:Enhancer_of_zeste_[E(z)]
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gptkbp:biologicalProcess
|
chromatin modification
regulation of transcription, DNA-templated
S-adenosyl-L-methionine-dependent methyltransferase activity
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gptkbp:catalyzes
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trimethylation of histone H3 at lysine 27
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gptkbp:complexity
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gptkb:Polycomb_Repressive_Complex_2
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gptkbp:domain
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gptkb:CXC_domain
gptkb:SANT_domain
SET domain
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gptkbp:Entrez_Gene_ID
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gptkb:FBgn0000575
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gptkbp:FlyBaseID
|
gptkb:FBgn0000575
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gptkbp:fullName
|
gptkb:Enhancer_of_zeste
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gptkbp:function
|
histone methyltransferase
|
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gptkbp:gene
|
E(z)
|
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gptkbp:GO_term
|
gptkb:GO:0006342
gptkb:GO:0018024
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|
https://www.w3.org/2000/01/rdf-schema#label
|
Drosophila E(z)
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gptkbp:interactsWith
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gptkb:Esc
gptkb:Su(z)12
Nurf55
|
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gptkbp:locatedOnChromosome
|
3R
|
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gptkbp:mutationAssociatedWith
|
homeotic transformations
|
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gptkbp:organism
|
gptkb:Drosophila_melanogaster
|
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gptkbp:orthologIn
|
gptkb:EZH2_(human)
|
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gptkbp:pathway
|
gptkb:Polycomb_group_(PcG)_pathway
|
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gptkbp:requires
|
embryonic development
maintenance of Hox gene repression
|
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gptkbp:role
|
epigenetic gene silencing
maintenance of transcriptional repression
|
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gptkbp:UniProtID
|
Q9V3F3
|
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gptkbp:bfsParent
|
gptkb:Ezh6
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gptkbp:bfsLayer
|
6
|