Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:amendedBy |
gptkb:histone_H2A
gptkb:histone_H3 |
| gptkbp:associatedWith |
epigenetic regulation
|
| gptkbp:catalyzes |
histone methylation
histone ubiquitination |
| gptkbp:component |
gptkb:Polycomb_Repressive_Complex_1
gptkb:Polycomb_Repressive_Complex_2 |
| gptkbp:discoveredIn |
gptkb:Drosophila_melanogaster
|
| gptkbp:enemyOf |
gptkb:Trithorax-group_proteins
|
| gptkbp:firstDescribed |
1978
|
| gptkbp:foundIn |
animals
fungi plants |
| gptkbp:function |
gene silencing
chromatin modification |
| gptkbp:hasMember |
gptkb:EED
gptkb:RBBP7 gptkb:CBX2 gptkb:EZH2 gptkb:PHC1 gptkb:RING1B gptkb:SUZ12 gptkb:RBBP4 BMI1 |
| https://www.w3.org/2000/01/rdf-schema#label |
Polycomb-group family
|
| gptkbp:involvedIn |
cancer progression
stem cell maintenance developmental regulation |
| gptkbp:namedAfter |
gptkb:Polycomb_gene
|
| gptkbp:regulates |
gptkb:Hox_genes
|
| gptkbp:bfsParent |
gptkb:Enhancer_of_zeste_homolog_2
|
| gptkbp:bfsLayer |
8
|