|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:BRPK
gptkb:PARK6
PARKIN-INTERACTING PROTEIN
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
|
|
gptkbp:discoveredBy
|
gptkb:Valina_L._Dawson
|
|
gptkbp:Entrez_Gene_ID
|
65018
|
|
gptkbp:enzymeCommissionNumber
|
EC 2.7.11.1
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
heart
|
|
gptkbp:fullName
|
gptkb:PTEN-induced_kinase_1
|
|
gptkbp:function
|
serine/threonine-protein kinase activity
mitochondrial quality control
|
|
gptkbp:gene
|
gptkb:PINK1
|
|
gptkbp:HGNC_ID
|
14581
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pink1
|
|
gptkbp:length
|
581 amino acids
|
|
gptkbp:locale
|
mitochondria
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1p36
|
|
gptkbp:molecularWeight
|
63 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:early-onset_Parkinson's_disease
|
|
gptkbp:OMIM
|
608309
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:pathway
|
gptkb:Parkinson's_disease_pathway
mitophagy pathway
|
|
gptkbp:PDB
|
gptkb:6EQI
|
|
gptkbp:phosphorylates
|
gptkb:Parkin
ubiquitin
|
|
gptkbp:RefSeq
|
gptkb:NM_032409
|
|
gptkbp:regulates
|
mitophagy
|
|
gptkbp:UniProtID
|
gptkb:Q9BXM7
|
|
gptkbp:bfsParent
|
gptkb:PARK6
gptkb:PINK1_gene
|
|
gptkbp:bfsLayer
|
8
|