Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:Ras
Rap small GTPases |
| gptkbp:alternativeName |
gptkb:PLCE1
PLC-epsilon phosphoinositide phospholipase C-epsilon |
| gptkbp:associatedWith |
gptkb:nephrotic_syndrome
esophageal cancer |
| gptkbp:domain |
gptkb:PH_domain
gptkb:EF-hand_domain C2 domain CDC25 homology domain Ras-associating domain |
| gptkbp:EC_number |
3.1.4.11
|
| gptkbp:encodedBy |
gptkb:PLCE1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
hydrolyzes phosphatidylinositol 4,5-bisphosphate
generates second messengers diacylglycerol and inositol trisphosphate |
| gptkbp:gene |
gptkb:PLCE1
|
| gptkbp:HGNC_ID |
9066
|
| gptkbp:involves |
signal transduction
|
| gptkbp:locatedOnChromosome |
10q23
|
| gptkbp:molecularWeight |
~230 kDa
|
| gptkbp:OMIM |
608414
|
| gptkbp:RefSeq |
NM_016341
|
| gptkbp:subcellularLocation |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:UniProtID |
Q9P212
|
| gptkbp:bfsParent |
gptkb:PLCĪµ
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Phospholipase C epsilon
|