Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
small GTPases
heterotrimeric G proteins |
| gptkbp:alternativeName |
gptkb:PLCE1
gptkb:PLC-epsilon-1 phosphoinositide phospholipase C-epsilon-1 |
| gptkbp:associatedWith |
nephrotic syndrome
esophageal squamous cell carcinoma |
| gptkbp:domain |
gptkb:PH_domain
gptkb:EF-hand_domain C2 domain CDC25 homology domain Ras-associating domain |
| gptkbp:encodedBy |
gptkb:PLCE1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
hydrolyzes phosphatidylinositol 4,5-bisphosphate
generates second messengers diacylglycerol and inositol trisphosphate |
| https://www.w3.org/2000/01/rdf-schema#label |
Phospholipase C-epsilon-1
|
| gptkbp:involvedIn |
signal transduction
|
| gptkbp:locatedOnChromosome |
10q23.33
|
| gptkbp:UniProtID |
Q9P212
|
| gptkbp:bfsParent |
gptkb:PLCĪµ
|
| gptkbp:bfsLayer |
7
|