Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:G-proteins
gptkb:Ras gptkb:Rho |
| gptkbp:alternativeName |
gptkb:phospholipase_C_epsilon_1
|
| gptkbp:associatedWith |
nephrotic syndrome
|
| gptkbp:catalyzes |
hydrolysis of PIP2
|
| gptkbp:domain |
gptkb:PH_domain
gptkb:EF-hand_domain C2 domain CDC25 homology domain Ras-associating domain X and Y catalytic domains |
| gptkbp:encodedBy |
gptkb:PLCE1_gene
|
| gptkbp:expressedIn |
gptkb:kidney
brain heart |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
phospholipase activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
PLC-epsilon-1
|
| gptkbp:involvedIn |
signal transduction
|
| gptkbp:locatedOnChromosome |
chromosome 10q23
|
| gptkbp:molecularWeight |
~250 kDa
|
| gptkbp:OMIM |
607398
|
| gptkbp:produces |
gptkb:inositol_trisphosphate_(IP3)
gptkb:diacylglycerol_(DAG) |
| gptkbp:UniProtID |
Q9P212
|
| gptkbp:bfsParent |
gptkb:PLCE1
|
| gptkbp:bfsLayer |
7
|