restless legs syndrome

GPTKB entity

Statements (54)
Predicate Object
gptkbp:instanceOf neurological disorder
gptkbp:affects sleep quality
gptkbp:alsoKnownAs gptkb:Willis-Ekbom_disease
gptkbp:cause gptkb:depression
genetic factors
anxiety
insomnia
daytime sleepiness
dopamine dysfunction
iron deficiency in brain
gptkbp:diagnosedBy clinical evaluation
exclusion of other conditions
patient history
gptkbp:firstDescribed 1672
https://www.w3.org/2000/01/rdf-schema#label restless legs syndrome
gptkbp:ICD-10_code G25.81
gptkbp:namedAfter gptkb:Karl-Axel_Ekbom
gptkb:Thomas_Willis
gptkbp:notableFor multiple sclerosis
rheumatoid arthritis
fibromyalgia
end-stage renal disease
pregnancy (especially third trimester)
gptkbp:prevalence increases with age
more common in women
gptkbp:relatedTo gptkb:periodic_limb_movement_disorder
gptkbp:riskFactor gptkb:Parkinson's_disease
gptkb:diabetes
family history
pregnancy
chronic kidney disease
iron deficiency
gptkbp:symptom relief with movement
uncomfortable sensations in legs
urge to move legs
worse in evening or night
worsening of symptoms at rest
gptkbp:treatment gptkb:benzodiazepines
lifestyle changes
anticonvulsants
iron supplements
opioids (in severe cases)
dopaminergic agents
gptkbp:triggeredBy gptkb:beer
certain medications
stress
caffeine
antipsychotics
sleep deprivation
antihistamines
antidepressants
gptkbp:bfsParent gptkb:gabapentin
gptkb:Sleepwalking
gptkbp:bfsLayer 6