|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:CD45
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:clinicalTrialPhase
|
yes
|
|
gptkbp:component
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
multiple researchers
|
|
gptkbp:encodes
|
gptkb:protein_tyrosine_phosphatase,_receptor_type_C
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000081237
5788
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
hematopoietic cells
lymphocytes
|
|
gptkbp:function
|
signal transduction
protein tyrosine phosphatase activity
regulation of T- and B-cell antigen receptor signaling
|
|
gptkbp:GOProcess
|
gptkb:immune_response
|
|
gptkbp:HGNC_ID
|
9666
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
1q31-q32
|
|
gptkbp:mutationAssociatedWith
|
gptkb:immunodeficiency
autoimmune diseases
|
|
gptkbp:OMIM
|
151460
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Ptprc
|
|
gptkbp:product
|
CD45 protein
|
|
gptkbp:proteinFamily
|
gptkb:protein_tyrosine_phosphatase_domain
gptkb:protein_tyrosine_phosphatase_family
fibronectin type III domain
|
|
gptkbp:RefSeq
|
NM_002838
|
|
gptkbp:UniProtID
|
P08575
|
|
gptkbp:bfsParent
|
gptkb:Leukocyte_common_antigen-related_protein
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PTPRC gene
|