|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CD45
gptkb:T200
gptkb:Leukocyte_common_antigen
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
immune system
|
|
gptkbp:domain
|
gptkb:protein_tyrosine_phosphatase_domain
fibronectin type III domain
|
|
gptkbp:encodes
|
gptkb:CD45
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000081237
19264 (mouse)
5788 (human)
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
hematopoietic cells
lymphocytes
|
|
gptkbp:function
|
protein tyrosine phosphatase activity
regulation of B-cell activation
regulation of T-cell activation
|
|
gptkbp:GO
|
GO:0004713 (protein tyrosine phosphatase activity)
GO:0042100 (B cell proliferation)
GO:0042110 (T cell activation)
|
|
gptkbp:HGNC_ID
|
9666
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ptprc
|
|
gptkbp:locatedOnChromosome
|
chromosome 1 (mouse)
chromosome 1q31-q32 (human)
|
|
gptkbp:mutationAssociatedWith
|
severe combined immunodeficiency (mouse)
|
|
gptkbp:OMIM
|
151460
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
PTPRC (human)
Ptprc (mouse)
|
|
gptkbp:proteinFamily
|
gptkb:protein_tyrosine_phosphatase_family
|
|
gptkbp:regulates
|
immune response
lymphocyte development
antigen receptor signaling
|
|
gptkbp:UniProtID
|
P06800 (mouse)
P08575 (human)
|
|
gptkbp:bfsParent
|
gptkb:PTPRC
|
|
gptkbp:bfsLayer
|
7
|