Statements (68)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gene
|
| gptkbp:associatedWith |
glioblastoma
breast cancer prostate cancer tumor suppression endometrial cancer |
| gptkbp:bornIn |
cancers
|
| gptkbp:code |
phosphatase
|
| gptkbp:diedIn |
cell cycle regulation
|
| gptkbp:established |
David_P._Lane
|
| gptkbp:firstClaim |
1997
|
| gptkbp:function |
lipid phosphatase
|
| gptkbp:hasRecognition |
biomarker
|
| gptkbp:hasRole |
apoptosis
|
| gptkbp:hasVariants |
PTEN_mutations
|
| https://www.w3.org/2000/01/rdf-schema#label |
PTEN gene
|
| gptkbp:interactsWith |
gptkb:EGFR
gptkb:PDGF p53 |
| gptkbp:involvedIn |
DNA repair
PI3K/AKT signaling pathway |
| gptkbp:is_evaluated_by |
various tissues
|
| gptkbp:isActiveIn |
AKT phosphorylation
|
| gptkbp:isAssociatedWith |
neurodevelopmental disorders
|
| gptkbp:isInvolvedIn |
cell differentiation
cellular homeostasis cellular metabolism cellular stress response immune response inflammation cellular proliferation cellular senescence tumor microenvironment cellular differentiation cellular responses to stimuli neurogenesis angiogenesis cell migration metastasis cellular signaling pathways cellular communication stem cell maintenance cellular signaling cellular repair mechanisms metabolic regulation cellular interactions cellular apoptosis cellular responses to stress cellular responses to electrical signals cellular responses to growth factors cellular responses to hormones cellular responses to light cellular responses to mechanical stress cellular responses to pH changes cellular responses to temperature changes cellular responses to nutrients cellular responses to oxygen levels cellular responses to ion concentrations cellular responses to damage |
| gptkbp:isLinkedTo |
autism spectrum disorders
|
| gptkbp:isPartOf |
tumor suppressor network
|
| gptkbp:isRegulatedBy |
microRNAs
|
| gptkbp:isStudiedIn |
cancer research
|
| gptkbp:isTargetedAt |
gene therapy
|
| gptkbp:isUtilizedFor |
normal cell function
|
| gptkbp:linkedTo |
gptkb:Cowden_syndrome
|
| gptkbp:locatedIn |
human chromosome 10
|
| gptkbp:regulates |
cell growth
|