|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
hPRL-R
prolactin receptor long form
prolactin receptor short form
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
prolactinoma
|
|
gptkbp:clinicalTrialPhase
|
prolactin receptor antibody test
|
|
gptkbp:discoveredIn
|
1988
|
|
gptkbp:encodes
|
prolactin receptor protein
|
|
gptkbp:Entrez_Gene_ID
|
5618
ENSG00000113494
|
|
gptkbp:expressedIn
|
gptkb:placenta
gptkb:prostate
gptkb:testis
liver
mammary gland
immune cells
|
|
gptkbp:fullName
|
gptkb:prolactin_receptor
|
|
gptkbp:function
|
mediates the actions of prolactin
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:9446
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PRLR
|
|
gptkbp:length
|
622
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
5p13.2
|
|
gptkbp:molecularWeight
|
70 kDa
|
|
gptkbp:mutationAssociatedWith
|
familial hyperprolactinemia
|
|
gptkbp:OMIM
|
601323
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Prlr
|
|
gptkbp:PDB
|
3NPZ
|
|
gptkbp:proteinFamily
|
type I cytokine receptor family
|
|
gptkbp:receptorFor
|
gptkb:prolactin
|
|
gptkbp:regulates
|
gptkb:progesterone
gptkb:prolactin
estrogen
recombinant human growth hormone
|
|
gptkbp:subcellularLocation
|
gptkb:cell_membrane
gptkb:cytoplasm
|
|
gptkbp:transmembraneDomains
|
1
|
|
gptkbp:type
|
gptkb:MAPK_pathway
gptkb:PI3K/AKT_pathway
gptkb:JAK-STAT_pathway
|
|
gptkbp:UniProtID
|
P16471
|
|
gptkbp:bfsParent
|
gptkb:JAK2
|
|
gptkbp:bfsLayer
|
7
|