Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:Cyclophilin_A
gptkb:Peptidyl-prolyl_cis-trans_isomerase_A |
| gptkbp:discoveredBy |
Fischer et al.
|
| gptkbp:discoveredIn |
1984
|
| gptkbp:EC_number |
5.2.1.8
|
| gptkbp:family |
gptkb:Cyclophilin_family
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
many eukaryotes |
| gptkbp:function |
catalyzes cis-trans isomerization of proline imidic peptide bonds in oligopeptides
|
| gptkbp:gene |
gptkb:PPIA
|
| https://www.w3.org/2000/01/rdf-schema#label |
PPIase A
|
| gptkbp:inhibitedBy |
gptkb:Cyclosporin_A
|
| gptkbp:interactsWith |
gptkb:HIV-1_capsid_protein
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:molecularWeight |
18 kDa
|
| gptkbp:PDB |
1CWA
|
| gptkbp:role |
immunosuppression
protein folding |
| gptkbp:structure |
single polypeptide chain
|
| gptkbp:UniProtID |
P62937
|
| gptkbp:bfsParent |
gptkb:CYPA
|
| gptkbp:bfsLayer |
7
|