|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:activatedBy
|
G-protein coupled receptors
|
|
gptkbp:affiliatedWith
|
gptkb:class_I_PI3K
|
|
gptkbp:alternativeName
|
gptkb:p110γ
gptkb:PIK3CG
gptkb:phosphoinositide_3-kinase_gamma
|
|
gptkbp:catalyzes
|
phosphorylation of phosphatidylinositol (4,5)-bisphosphate
|
|
gptkbp:EC_number
|
2.7.1.153
|
|
gptkbp:encodedBy
|
gptkb:PIK3CG_gene
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
heart
endothelial cells
|
|
gptkbp:formsComplexWith
|
gptkb:p101
gptkb:p84
|
|
gptkbp:hasCatalyticSubunit
|
gptkb:p110γ
|
|
gptkbp:hasRole
|
allergic response
cardiac contractility
chemotaxis
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PI3Kgamma
|
|
gptkbp:inhibitedBy
|
gptkb:IPI-549
AS-605240
CZC24832
|
|
gptkbp:involvedIn
|
cell signaling
inflammation
immune response
|
|
gptkbp:locatedOnChromosome
|
7q22.3
|
|
gptkbp:molecularWeight
|
126 kDa (p110γ subunit)
|
|
gptkbp:produces
|
gptkb:phosphatidylinositol_(3,4,5)-trisphosphate
|
|
gptkbp:target
|
pharmacological inhibitors
|
|
gptkbp:UniProtID
|
gptkb:P48736
|
|
gptkbp:bfsParent
|
gptkb:Pik3cg
|
|
gptkbp:bfsLayer
|
6
|