Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activity |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
| gptkbp:associatedWith |
cardiovascular diseases
inflammatory diseases |
| gptkbp:component |
gptkb:phosphoinositide_3-kinase_gamma_complex
|
| gptkbp:encodedBy |
gptkb:PIK3CG_gene
|
| gptkbp:enzymeClassification |
gptkb:EC_2.7.1.153
|
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:function |
catalytic subunit of PI3Kγ
|
| https://www.w3.org/2000/01/rdf-schema#label |
p110γ
|
| gptkbp:interactsWith |
gptkb:p101
gptkb:p84 |
| gptkbp:involvedIn |
cell signaling
immune response |
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:molecularWeight |
~110 kDa
|
| gptkbp:regulates |
activated by Ras
activated by Gβγ subunits |
| gptkbp:target |
PI3Kγ inhibitors
|
| gptkbp:bfsParent |
gptkb:PIK3CG
|
| gptkbp:bfsLayer |
5
|