Statements (26)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
gptkb:phosphatidylinositol-4,5-bisphosphate_3-kinase_catalytic_subunit_gamma_isoform
gptkb:PIK3CG gptkb:PI3Kγ |
gptkbp:encodedBy |
gptkb:PIK3CG_gene
|
gptkbp:enzymeCommissionNumber |
2.7.1.153
|
gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
gptkbp:function |
involved in signal transduction
regulates immune cell function catalyzes phosphorylation of phosphatidylinositol |
https://www.w3.org/2000/01/rdf-schema#label |
PI3-kinase p110 gamma
|
gptkbp:interactsWith |
gptkb:G_protein_beta-gamma_subunits
p101 regulatory subunit p84 regulatory subunit |
gptkbp:involvedIn |
inflammation
immune response chemotaxis |
gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
gptkbp:molecularWeight |
~110 kDa
|
gptkbp:partOf |
gptkb:phosphoinositide_3-kinase_complex
|
gptkbp:target |
pharmacological inhibitors
|
gptkbp:UniProtID |
gptkb:P48736
|
gptkbp:bfsParent |
gptkb:PIK3CG_(p110γ)
|
gptkbp:bfsLayer |
6
|