|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
PGAM-B
phosphoglycerate mutase, brain
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:anemia
|
|
gptkbp:cofactor
|
2,3-bisphosphoglycerate
|
|
gptkbp:conservedIn
|
PGAM domain
|
|
gptkbp:encodedBy
|
PGAM1 gene
|
|
gptkbp:Entrez_Gene_ID
|
5223
|
|
gptkbp:enzyme
|
true
|
|
gptkbp:enzymeCommissionNumber
|
5.4.2.1
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
liver
erythrocytes
|
|
gptkbp:foundIn
|
human genome
|
|
gptkbp:fullName
|
Phosphoglycerate mutase 1
|
|
gptkbp:function
|
catalyzes the conversion of 3-phosphoglycerate to 2-phosphoglycerate in glycolysis
phosphoglycerate mutase activity
|
|
gptkbp:GOProcess
|
glycolytic process
|
|
gptkbp:hasIsoform
|
gptkb:PGAM2
|
|
gptkbp:HGNC_ID
|
8886
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PGAM1
|
|
gptkbp:interactsWith
|
gptkb:PKM
gptkb:ENO1
|
|
gptkbp:locatedOnChromosome
|
10q24.1
|
|
gptkbp:location
|
gptkb:cytoplasm
cytosol
|
|
gptkbp:molecularWeight
|
29 kDa
|
|
gptkbp:mutationAssociatedWith
|
phosphoglycerate mutase deficiency
|
|
gptkbp:OMIM
|
172250
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
gptkb:Rattus_norvegicus
|
|
gptkbp:participatedIn
|
glycolysis
|
|
gptkbp:pathway
|
carbohydrate metabolism
|
|
gptkbp:PDB
|
1YFK
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:RefSeq
|
NM_002629
|
|
gptkbp:regulates
|
regulated by phosphorylation
|
|
gptkbp:reviewedBy
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:UniProt
|
|
gptkbp:significance
|
deficiency causes glycogen storage disease type X
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
|
|
gptkbp:tissue_specificity
|
ubiquitous, high in muscle and brain
|
|
gptkbp:UniProtID
|
P18669
|
|
gptkbp:bfsParent
|
gptkb:phosphoglycerate_mutase
|
|
gptkbp:bfsLayer
|
8
|